Usage
simulate_sample_genotype(sample_cois, locus_allele_dist, internal_relatedness)
Arguments
- sample_cois
Numeric vector indicating the multiplicity of infection
for each biological sample
- locus_allele_dist
Allele frequencies – simplex parameter of a
multinomial distribution
- internal_relatedness
numeric 0-1 indicating the probability for a
strain's allele to come from an existing lineage within host
Details
Simulates sampling the genetics at a single locus given an allele
frequency distribution and a vector of sample COIs